Unexpected discovery of hemoglobinopathy C/β° thalassemia
نویسندگان
چکیده
منابع مشابه
Hemoglobinopathy and thalassemia detection
In humans, two pairs of unlike globin chains combine with four heme groups to form hemoglobin (Hb), a protein that is carried by red cells and picks up oxygen in the lungs and delivers it to the peripheral tissues. One of the globin chain pairs in hemoglobin is always alpha (with the exception of the very first weeks of embryogenesis), while the second pair is ―nonalpha.‖ That is, it can be mad...
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The small mean corpuscular volume (MCV) of red blood cell is one of the indicators for thalassemia and hemoglobinopathy screening. As other screening methods, it may have some degrees of limitation. The retrospective study was performed among 104 patients who had various kinds of thalassemia or hemoglobinopathy despite having normal hemoglobin (Hb) concentration and normal mean corpuscular volu...
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Standard hematologic methods were used.2 In vitro sickling tests were carried out using the method of 1)aiand and Castle.’ Fetal hemoglobin was estimated by the alkali denaturation technic of Singer, Chernoff and Singer.’ Filter-paper electrophoresis of hemoglobin was performed in a horizontal tank using barbitone buffer pH 8.6 and ionic strength about 0.02. The technic is described in detail e...
متن کاملA new hereditary hemoglobinopathy (the Lepore trait) and its interaction with thalassemia trait.
By PARK S. GERALD AND Louis K. DIAMOND T HIS REPORT details our experiences with a new hemoglobinopathy which we have named the “Lepore trait.” This condition was discovered during a recent survey of the relatives of thalassemia major children.1 The mother of a child with clinical thalassemia major was found to possess a new abnormal hemoglobin (which we have named the Lepore hemoglobin) demons...
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We report the case of multiple myeloma of unexpected discovery in an old patient admitted to the emergency department of cardiomyopathy. This observation emphasizes the need for exploring any anemia before linking it to heart failure or kidney disease. Serum protein electrophoresis remains crucial especially in the elderly patients.
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ژورنال
عنوان ژورنال: Clinical Case Reports
سال: 2018
ISSN: 2050-0904
DOI: 10.1002/ccr3.1815